“Spravato Ruined My Life”: Side Effects and What to Do

Ritesha Krishnappa • November 11, 2025

For many patients, Spravato (esketamine nasal spray) represents a lifeline when traditional antidepressants fall short. However, no treatment is without risk, and you may have stumbled upon online stories that read “Spravato ruined my life.” In this article, we’ll explore:


  1. Why some patients have negative experiences

  2. Common and rare side effects of Spravato

  3. How to minimize risks

  4. When to seek help

  5. What makes treatment at Elevium different

1. Why Do “Spravato Ruined My Life” Stories Exist?

High Expectations vs. Reality

Spravato often produces fast results - but not for everyone. Stories of dramatic transformation can raise expectations. When relief doesn’t come quickly, or side effects occur, patients may feel disappointed and share their frustration online.

Patients Are Already Vulnerable

Spravato is prescribed for treatment-resistant depression, meaning patients have typically endured years of struggle. Any negative experience can feel especially intense.

Important Perspective

Social media tends to amplify the extremes. Our goal at Elevium is to provide balance-transparent information and clinical support that empower you to make informed choices.

2. Common Side Effects of Spravato

Spravato is administered in-clinic under physician supervision, and most side effects resolve within a few hours.

Side Effect Frequency What Elevium Does
Dissociation (feeling disconnected) 25–40% of sessions You’ll be monitored in a private, calming room with clinical staff nearby
Dizziness / Vertigo 10–20% We recommend arriving hydrated and resting post-session
Nausea / Vomiting 5–10% Antiemetics available upon request
Sedation / Fatigue 15–30% Patients are encouraged to rest after each treatment
Increased Blood Pressure 35–50% Vitals are monitored before, during, and after sessions

At Elevium, all sessions follow REMS (Risk Evaluation and Mitigation Strategy) protocols, with built-in observation periods to ensure your safety.

3. Rare but Serious Risks

While rare, more serious complications can occur:


  • Prolonged dissociation or hallucinations
  • Significant blood pressure changes
  • Potential for misuse (esketamine is a Schedule III substance)


We mitigate these risks through:


  • Continuous monitoring by licensed clinical staff
  • Emergency response protocols on-site
  • Controlled, in-clinic-only access-no take-home usage

How Elevium Minimizes Your Risk

Your care team at Elevium includes board-certified psychiatrists and licensed therapists who work together to tailor your care plan.


Our approach includes:


  • Comprehensive psychiatric evaluation
  • Personalized dosing and scheduling
  • BDI-II and PHQ-9 assessments to track progress
  • Optional integration with psychotherapy, TMS, or medication management
  • On-site clinical supervision every step of the way


We’ll also ensure you’re well-supported before, during, and after each visit.

5. When to Seek Help Immediately

Please contact Elevium or seek emergency care if you experience:


  • Chest pain or severe headache
  • Persistent confusion or dissociation
  • Suicidal thoughts or intentions


We're here to support you, but urgent situations require immediate attention.

A man with glasses and a beard is wearing a blue suit and smiling.

Making an Informed Choice with Elevium

Sensational headlines like “Spravato ruined my life” can create unnecessary fear. At Elevium, our mission is to offer safe, evidence-based, and compassionate care that works with you - not just for you.


If you're considering Spravato:


  • We'll guide you through every step
  • We’ll tailor your plan to your personal goals
  • You’ll always have someone to talk to
Spravato Treatment at Elevium

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